Precision Temperature Maintenance
Biopharmaceutical distribution requires unwavering temperature consistency. Zerothermo VIP systems provide exceptional thermal resistance with minimal wall thickness, maximizing payload space while maintaining critical temperatures for up to 120+ hours.
Essential for routine vaccines (influenza, rabies, hepatitis), monoclonal antibodies, and insulin. Our fumed silica VIP insulation blocks ambient heat ingress even in tropical climates (up to +45 °C), preventing thermal degradation, protein denaturation, and accidental freeze damage caused by uneven passive cooling packs.
Tailored for mRNA vaccines, viral vectors, cellular therapeutics, and clinical specimens requiring dry ice pellets or -70 °C phase change materials (PCMs). Zerothermo VIPs mitigate rapid dry-ice sublimation, extending autonomous shipping transit time beyond 96 to 144 hours across global air cargo routes.
Engineered for regenerative stem cells, biological tissues, and specialized genomics. Multi-layer high-barrier metallized films paired with micro-porous silica cores minimize heat transfer at cryogenic thresholds, significantly lowering liquid nitrogen boil-off and container tare weights.
Engineering Superiority
Compared to traditional polyurethane (PU) foam, expanded polystyrene (EPS), or fiberglass insulation, Zerothermo Vacuum Insulation Panels provide up to 10 times higher thermal resistance with only a fraction of the material thickness.
Certified thermal conductivity ≤ 0.0045 W/(m·K), delivering maximum insulation barrier at minimal mass.
Thin profile (5mm - 50mm) increases usable container payload by 30% to 60%, drastically reducing air freight and distribution overheads.
Inorganic pressed fumed silica core is fully recyclable, non-ozone depleting, and certified under RoHS & REACH standards by SGS.
Enclosed in multi-layer metallized barrier film with specialized getters to ensure vacuum integrity for decades of reusable shipper deployments.
Zerothermo VIP for Vaccine Passive Cooler Assembly (VIP + PCM)
Data-Driven Quality
Rigorous mechanical testing, density validation, and thermal conductivity profiling ensure each vacuum insulation panel meets stringent pharmaceutical cold chain criteria.
| Test Parameter | Unit | Standard Value |
|---|---|---|
| Thermal Conductivity | W/(m·K) | ≤ 0.0045 |
| Operating Temperature Rating | ℃ | -80 to +70 |
| Core Material Density | kg/m³ | 180 ± 10 |
| Compressive Strength | kPa | ≥ 100 |
| Tensile Strength | kPa | ≥ 80 |
| Puncture Resistance Strength | N | ≥ 14 |
| Internal Vacuum Level | Pa | ≤ 0.1 |
| Environmental Safety Cert. | - | RoHS & REACH (SGS) |
| Dimensional Parameter | Unit | Manufacturing Limits |
|---|---|---|
| Panel Length (L) | mm | 300 – 1200 (Custom available) |
| Panel Width (W) | mm | 300 – 800 (Custom available) |
| Panel Thickness (T) | mm | 5 – 80 (5, 10, 15, 20, 25, 30, 50) |
| Length/Width Tolerance | mm | -3 / +2 (L/W ≤ 500mm) |
| Thickness Tolerance | mm | ± 1.0 (Thickness ≤ 30mm) |
| Barrier Film Structure | Type | Aluminized / PET / Multi-layer Seal |
| Edge Sealing Method | Type | Back Seal / Four-Side Folded Seal |
| Export Transport Packaging | - | Fumigated Wooden Crate + Pallet |
Benchmark Comparison
See how Zerothermo Fumed Silica VIP outclasses traditional thermal insulation materials in insulation value and payload retention for life science cold chains.
| Insulation Technology | Thermal Conductivity (W/m·K) | Required Thickness for R-20 Value | Weight / Payload Impact | Cold Chain Viability (2-8°C / -70°C) |
|---|---|---|---|---|
| Zerothermo Fumed Silica VIP | 0.0040 – 0.0045 | ~15 – 20 mm | Minimal weight; maximizes internal payload up to 60% | Exceptional (120+ Hours Holdover) |
| Aerogel Blanket / Insulation | 0.015 – 0.020 | ~70 mm | Moderate; dust particles require containment | Moderate (Higher cost, thick build) |
| Rigid Polyurethane Foam (PUR/PIR) | 0.022 – 0.028 | ~100 mm | Bulky; causes large outer box footprint | Standard (24 – 48 Hours max) |
| Expanded Polystyrene (EPS Foam) | 0.035 – 0.040 | ~150 mm | Extreme bulk; high freight shipping volumetric cost | Short distance only (< 24 Hours) |
| Fiberglass / Mineral Wool | 0.038 – 0.045 | ~180 mm | Heavy, permeable to atmospheric humidity | Unsuitable for strict vaccine cold boxes |
Precision Manufacturing Process
From raw nano-silica compounding to multi-stage helium laser leakage inspection, our clean-room facilities adhere to the highest international quality assurance benchmarks.
Precise blending of hydrophobic fumed silica, opacifiers, and structural reinforcing fibers.
Automated hydraulic compression forming uniform microporous core boards with controlled density (180 kg/m³).
Laser-guided CNC sizing to exact customer dimensions and enveloping inside non-woven breathable fabric.
Multi-chamber thermal drying to thoroughly eliminate residual moisture, volatile organics, and microscopic debris.
Enclosure within high-density multilayer metallized barrier foil and getter addition for long-term gas absorption.
Automated high-vacuum evacuation down to ≤ 0.1 Pa accompanied by immediate precision thermal fusion welding.
Multi-day atmospheric aging validation, laser surface deflection testing, and conductivity audits.
Protected edge flap tape folding, protective carton cushioning, and heavy-duty palletized export container packaging.
Product Center

Engineered specifically for vaccine shippers, ultra-low temperature freezers, and cold boxes (2–8 °C and −70 °C).

Large-format panels designed for refrigerated sea containers, temperature-controlled air cargo LD3/RKN units.

Curved, slotted, round, and cutout profiles laminated with protective scratch-resistant PET outer films.

High-efficiency thermal barrier for laboratory cryostats, blood banks, and deep-freeze preservation units.

Ultra-thin thermal runaway prevention barrier for new energy vehicle power battery packs.

Flexible high-temperature thermal barrier for industrial water heaters, heating tanks, and pipelines.

A1-class non-combustible microporous panels designed for fireproof elevator doors and security gates.

Round and customizable flexible high-temperature insulation mats for complex industrial geometries.
Corporate Strength & Innovation
Zerothermo Technology Co., Ltd. is a world-class high-tech enterprise specializing in the research, development, and mass manufacturing of advanced thermal insulation materials. With over 400,000 square meters of intelligent production workshop space across 3 modern industrial bases, Zerothermo stands at the forefront of the global energy-saving and nano-thermal barrier industry.
Backed by an engineering talent pool of more than 330 R&D scientists and technical specialists and an overall workforce exceeding 1,100 employees, our company holds numerous domestic and international patents in fumed silica microporous cores, high-barrier composite films, vacuum sealing machinery, and tempered vacuum insulated glass.
While our core cold chain solutions safeguard life-saving vaccines, biological reagents, and temperature-sensitive pharmaceuticals worldwide, Zerothermo also manufactures advanced energy-conservation solutions for architectural curtain walls (Tempered Vacuum Glass), new energy automotive battery packs, home and commercial refrigeration appliances, and high-temperature industrial furnaces.
Read More About UsGlobal Assurance
From rapid CNC prototyping to full-scale monthly capacity exceeding 50,000 square meters, we provide end-to-end reliability for cold chain logistics providers.

ISO9001, ISO14001, RoHS, and REACH certified manufacturing with 100% individual panel thermal validation.

Custom thickness (5-80mm), 2D/3D shapes, edge folds, and rapid prototyping sample delivery within 3-7 business days.

Monthly output capacity of 50,000+ sqm ensures stable delivery schedules for major commercial rollouts.

Seamless logistics support with flexible Incoterms (FOB, CIF, DDP) shipping via major ports including Shanghai and Shenzhen.
Commercial Terms & Supply
We provide flexible commercial arrangements to accommodate pharmaceutical distributors, cooler box OEMs, cold chain container fabricators, and clinical research organizations.
Monthly Supply Ability: 50,000 Square Meters / Month
Export Loading Ports: Shanghai, Shenzhen, Ningbo (China)
Pricing & Trade Terms: FOB, CFR, CIF, EXW, DDP, DDU
Accepted Currencies: USD, EUR, JPY, CAD, CNY, AUD, GBP
Payment Terms: T/T, L/C, D/P, D/A, Western Union
Every export shipment is wrapped in puncture-resistant film, padded with shock-absorbing foam corners, and crated in heavy-duty wooden pallet enclosures to ensure zero damage during international ocean and air freight.
Reinforced Export Cartons
Palletized Fumigated Crates
Multi-Sector Versatility
Beyond biopharmaceutical vaccine distribution, Zerothermo’s nano-insulation technologies empower high-performance energy conservation across diverse industries.
Vaccine courier boxes, blood transport cases, portable clinical cooler bags, ultra-low temperature freezers, mobile vaccine stations, and refrigerated pharmacy displays.
Ultra-low energy passive houses, exterior wall retrofitting, balcony thermal bridge breaks, floor underlayment, and energy-efficient tempered vacuum architectural glazing.
Industrial furnaces, ladle back-up insulation, metallurgy thermal barriers, fuel cells, aerospace heat shields, and certified fireproof elevator door assemblies.
Real-World Deployments
Frequently Asked Questions
Key technical insights on thermal performance, holdover duration, cold bridge prevention, and regulatory compliance.
Knowledge & Events
Get In Touch
Our technical engineering team can assist you with thermal holdover modeling, custom dimensions, sample testing requests, and global logistics quotations.

