Next-Gen Nano Thermal Protection

Vaccine Cold Chain Insulation Panels: VIP for 2–8 °C and −70 °C Shipping

Ultra-thin, high-barrier Vacuum Insulation Panels (VIPs) engineered with fumed silica cores delivering thermal conductivity ≤ 0.0045 W/m·K. Ensure uncompromised temperature stability across long-haul biopharmaceutical logistics.

330 R&D Engineers
330+
R&D Engineers
1100 Employees
1,100+
Global Employees
3 Modern Manufacturing Hubs
3+
Production Bases
400,000 sqm Workshop
400,000㎡
Intelligent Workshop

Precision Temperature Maintenance

Specialized Thermal Solutions for 2–8 °C and −70 °C Cold Chains

Biopharmaceutical distribution requires unwavering temperature consistency. Zerothermo VIP systems provide exceptional thermal resistance with minimal wall thickness, maximizing payload space while maintaining critical temperatures for up to 120+ hours.

2 °C to 8 °C Standard Vaccine Logistics

Essential for routine vaccines (influenza, rabies, hepatitis), monoclonal antibodies, and insulin. Our fumed silica VIP insulation blocks ambient heat ingress even in tropical climates (up to +45 °C), preventing thermal degradation, protein denaturation, and accidental freeze damage caused by uneven passive cooling packs.

−20 °C to −70 °C Ultra-Low Temperature (ULT)

Tailored for mRNA vaccines, viral vectors, cellular therapeutics, and clinical specimens requiring dry ice pellets or -70 °C phase change materials (PCMs). Zerothermo VIPs mitigate rapid dry-ice sublimation, extending autonomous shipping transit time beyond 96 to 144 hours across global air cargo routes.

Deep Cryogenic & Liquid Nitrogen (-150 °C)

Engineered for regenerative stem cells, biological tissues, and specialized genomics. Multi-layer high-barrier metallized films paired with micro-porous silica cores minimize heat transfer at cryogenic thresholds, significantly lowering liquid nitrogen boil-off and container tare weights.

Engineering Superiority

Why Vacuum Insulation Panels (VIPs) Redefine Cold Chain Performance

Compared to traditional polyurethane (PU) foam, expanded polystyrene (EPS), or fiberglass insulation, Zerothermo Vacuum Insulation Panels provide up to 10 times higher thermal resistance with only a fraction of the material thickness.

✓
Ultra-Low Thermal Conductivity:

Certified thermal conductivity ≤ 0.0045 W/(m·K), delivering maximum insulation barrier at minimal mass.

✓
Payload Volume Optimization:

Thin profile (5mm - 50mm) increases usable container payload by 30% to 60%, drastically reducing air freight and distribution overheads.

✓
100% Non-Toxic & Sustainable:

Inorganic pressed fumed silica core is fully recyclable, non-ozone depleting, and certified under RoHS & REACH standards by SGS.

✓
50+ Years Service Longevity:

Enclosed in multi-layer metallized barrier film with specialized getters to ensure vacuum integrity for decades of reusable shipper deployments.

Vaccine Insulation Cooler Box with VIP Panels

Zerothermo VIP for Vaccine Passive Cooler Assembly (VIP + PCM)

Data-Driven Quality

Technical Performance & Dimensional Specifications

Rigorous mechanical testing, density validation, and thermal conductivity profiling ensure each vacuum insulation panel meets stringent pharmaceutical cold chain criteria.

Core Performance Parameters

Test Parameter Unit Standard Value
Thermal Conductivity W/(m·K) ≤ 0.0045
Operating Temperature Rating ℃ -80 to +70
Core Material Density kg/m³ 180 ± 10
Compressive Strength kPa ≥ 100
Tensile Strength kPa ≥ 80
Puncture Resistance Strength N ≥ 14
Internal Vacuum Level Pa ≤ 0.1
Environmental Safety Cert. - RoHS & REACH (SGS)

Dimensional & Manufacturing Specs

Dimensional Parameter Unit Manufacturing Limits
Panel Length (L) mm 300 – 1200 (Custom available)
Panel Width (W) mm 300 – 800 (Custom available)
Panel Thickness (T) mm 5 – 80 (5, 10, 15, 20, 25, 30, 50)
Length/Width Tolerance mm -3 / +2 (L/W ≤ 500mm)
Thickness Tolerance mm ± 1.0 (Thickness ≤ 30mm)
Barrier Film Structure Type Aluminized / PET / Multi-layer Seal
Edge Sealing Method Type Back Seal / Four-Side Folded Seal
Export Transport Packaging - Fumigated Wooden Crate + Pallet

Benchmark Comparison

Thermal Conductivity & Thickness Advantage

See how Zerothermo Fumed Silica VIP outclasses traditional thermal insulation materials in insulation value and payload retention for life science cold chains.

Insulation Technology Thermal Conductivity (W/m·K) Required Thickness for R-20 Value Weight / Payload Impact Cold Chain Viability (2-8°C / -70°C)
Zerothermo Fumed Silica VIP 0.0040 – 0.0045 ~15 – 20 mm Minimal weight; maximizes internal payload up to 60% Exceptional (120+ Hours Holdover)
Aerogel Blanket / Insulation 0.015 – 0.020 ~70 mm Moderate; dust particles require containment Moderate (Higher cost, thick build)
Rigid Polyurethane Foam (PUR/PIR) 0.022 – 0.028 ~100 mm Bulky; causes large outer box footprint Standard (24 – 48 Hours max)
Expanded Polystyrene (EPS Foam) 0.035 – 0.040 ~150 mm Extreme bulk; high freight shipping volumetric cost Short distance only (< 24 Hours)
Fiberglass / Mineral Wool 0.038 – 0.045 ~180 mm Heavy, permeable to atmospheric humidity Unsuitable for strict vaccine cold boxes

Precision Manufacturing Process

State-of-the-Art Intelligent VIP Production Line

From raw nano-silica compounding to multi-stage helium laser leakage inspection, our clean-room facilities adhere to the highest international quality assurance benchmarks.

01

Nano Material Mixing

Precise blending of hydrophobic fumed silica, opacifiers, and structural reinforcing fibers.

02

Core Mold Pressing

Automated hydraulic compression forming uniform microporous core boards with controlled density (180 kg/m³).

03

Precision Core Cutting

Laser-guided CNC sizing to exact customer dimensions and enveloping inside non-woven breathable fabric.

04

High-Temp Dehydration

Multi-chamber thermal drying to thoroughly eliminate residual moisture, volatile organics, and microscopic debris.

05

High-Barrier Film Sealing

Enclosure within high-density multilayer metallized barrier foil and getter addition for long-term gas absorption.

06

Deep Vacuum Extraction

Automated high-vacuum evacuation down to ≤ 0.1 Pa accompanied by immediate precision thermal fusion welding.

07

100% Leakage Inspection

Multi-day atmospheric aging validation, laser surface deflection testing, and conductivity audits.

08

Corner Folding & Packing

Protected edge flap tape folding, protective carton cushioning, and heavy-duty palletized export container packaging.

Product Center

Customized Vacuum Insulation Panel Solutions

Browse All Products
Low Temperature Cold Chain Logistics Fumed Silica Vacuum Insulation Panel

Cold Chain Fumed Silica VIP

Engineered specifically for vaccine shippers, ultra-low temperature freezers, and cold boxes (2–8 °C and −70 °C).

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Big or Customized Size fumed silica vacuum insulation panel for cooler container

Large Size VIP for Containers

Large-format panels designed for refrigerated sea containers, temperature-controlled air cargo LD3/RKN units.

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Fumed Silica Special Shaped VIPs Vacuum Insulation Panel with PET Film

Special Shaped VIP with PET Film

Curved, slotted, round, and cutout profiles laminated with protective scratch-resistant PET outer films.

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Low thermal conductivity VIP fumed silica vacuum insulation panel with PET film

Low Conductivity VIP Panels

High-efficiency thermal barrier for laboratory cryostats, blood banks, and deep-freeze preservation units.

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New Energy Vehicles Battery Insulation Blanket Layer

EV Battery Insulation Blanket

Ultra-thin thermal runaway prevention barrier for new energy vehicle power battery packs.

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High Temperature Nano Microporous Water Heater Tank Insulation Blanket Wrap

High-Temp Microporous Blanket

Flexible high-temperature thermal barrier for industrial water heaters, heating tanks, and pipelines.

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High Temperature Nano Microporous Insulated Panels For Elevator Fireproof Door

Elevator Fireproof Door Panels

A1-class non-combustible microporous panels designed for fireproof elevator doors and security gates.

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Custom Round High temperature Flexible Nano insulation blanket Mat panels

Custom Flexible Nano Blanket Mat

Round and customizable flexible high-temperature insulation mats for complex industrial geometries.

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Corporate Strength & Innovation

Zerothermo Technology Co., Ltd.

Zerothermo Technology Co., Ltd. is a world-class high-tech enterprise specializing in the research, development, and mass manufacturing of advanced thermal insulation materials. With over 400,000 square meters of intelligent production workshop space across 3 modern industrial bases, Zerothermo stands at the forefront of the global energy-saving and nano-thermal barrier industry.

Backed by an engineering talent pool of more than 330 R&D scientists and technical specialists and an overall workforce exceeding 1,100 employees, our company holds numerous domestic and international patents in fumed silica microporous cores, high-barrier composite films, vacuum sealing machinery, and tempered vacuum insulated glass.

While our core cold chain solutions safeguard life-saving vaccines, biological reagents, and temperature-sensitive pharmaceuticals worldwide, Zerothermo also manufactures advanced energy-conservation solutions for architectural curtain walls (Tempered Vacuum Glass), new energy automotive battery packs, home and commercial refrigeration appliances, and high-temperature industrial furnaces.

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Zerothermo Technology Production Base
Zerothermo Cleanroom Vacuum Packaging
Zerothermo Automated Manufacturing Hub

Global Assurance

Why Global Pharma & Logistics Leaders Choose Zerothermo

From rapid CNC prototyping to full-scale monthly capacity exceeding 50,000 square meters, we provide end-to-end reliability for cold chain logistics providers.

World-Class Quality Standards

World-Class Quality

ISO9001, ISO14001, RoHS, and REACH certified manufacturing with 100% individual panel thermal validation.

Custom Tailored Solutions

Swift Customization

Custom thickness (5-80mm), 2D/3D shapes, edge folds, and rapid prototyping sample delivery within 3-7 business days.

Scalable Production Capacity

Scalable Capacity

Monthly output capacity of 50,000+ sqm ensures stable delivery schedules for major commercial rollouts.

Streamlined Logistics Global Reach

Global Reach

Seamless logistics support with flexible Incoterms (FOB, CIF, DDP) shipping via major ports including Shanghai and Shenzhen.

Commercial Terms & Supply

Business Conditions & Export Packaging

We provide flexible commercial arrangements to accommodate pharmaceutical distributors, cooler box OEMs, cold chain container fabricators, and clinical research organizations.

Monthly Supply Ability: 50,000 Square Meters / Month

Export Loading Ports: Shanghai, Shenzhen, Ningbo (China)

Pricing & Trade Terms: FOB, CFR, CIF, EXW, DDP, DDU

Accepted Currencies: USD, EUR, JPY, CAD, CNY, AUD, GBP

Payment Terms: T/T, L/C, D/P, D/A, Western Union

Every export shipment is wrapped in puncture-resistant film, padded with shock-absorbing foam corners, and crated in heavy-duty wooden pallet enclosures to ensure zero damage during international ocean and air freight.

VIP Export Packaging Wooden Carton

Reinforced Export Cartons

Palletized VIP Transportation

Palletized Fumigated Crates

Multi-Sector Versatility

Comprehensive Vacuum Insulation Applications

Beyond biopharmaceutical vaccine distribution, Zerothermo’s nano-insulation technologies empower high-performance energy conservation across diverse industries.

Pharmaceutical Cold Chain Solutions
Pharma Cold Chain Icon

Pharma Cold Chain

Vaccine courier boxes, blood transport cases, portable clinical cooler bags, ultra-low temperature freezers, mobile vaccine stations, and refrigerated pharmacy displays.

Green Architecture and Building VIP
Architecture Icon

Green Architecture

Ultra-low energy passive houses, exterior wall retrofitting, balcony thermal bridge breaks, floor underlayment, and energy-efficient tempered vacuum architectural glazing.

High-Temperature Industrial Thermal Barriers
High-Temp Icon

High-Temp Industry

Industrial furnaces, ladle back-up insulation, metallurgy thermal barriers, fuel cells, aerospace heat shields, and certified fireproof elevator door assemblies.

Real-World Deployments

Proven Cold Chain & Insulation Case Studies

Explore All Cases
MultiMicro Technology Cleanroom Integration

MultiMicro Cleanroom Project

Integration of high-performance thermal insulation panels for temperature-controlled laboratories.

Precision Thermal Barrier MultiMicro

Precision Laboratory Thermal Barrier

Custom VIP implementation maintaining ±0.5 °C chamber tolerances for sensitive biological assays.

Nanchong Campus Thermal Renovation

Nanchong High School Retrofit

Large-scale architectural energy efficiency upgrade using nano-microporous exterior insulation.

Vaccine Insulation Cooler Box Field Deployment

Global Vaccine Shipper Boxes

Autonomous 96-hour passive vaccine transport system engineered for extreme cross-border temperature profiles.

Frequently Asked Questions

Vacuum Insulation Panels (VIP) in Vaccine Cold Chains

Key technical insights on thermal performance, holdover duration, cold bridge prevention, and regulatory compliance.

How do Vacuum Insulation Panels ensure strict 2–8 °C and −70 °C holdover times during international freight?
VIP panels virtually eliminate heat conduction and convection by evacuating atmospheric air from within a nanoporous fumed silica matrix. With thermal conductivity down to 0.0045 W/m·K, they provide up to 10 times higher thermal resistance than PU or EPS. When paired with appropriate Phase Change Materials (PCMs) or dry ice, they stabilize the internal payload zone for 72 to 144+ hours without requiring active motorized refrigeration.
What makes fumed silica core superior to glass fiber cores for pharmaceutical cold chain shipping?
Fumed silica possesses an extremely small pore size (approx. 20–50 nm), which is smaller than the mean free path of air molecules at atmospheric pressure. Even if the vacuum barrier experiences micro-permeation over decades, fumed silica maintains a relatively low thermal conductivity (~0.018 W/m·K), preventing catastrophic temperature runaway. In contrast, fiberglass cores lose up to 80% of their insulating performance immediately upon vacuum loss. Furthermore, fumed silica is 100% non-toxic, non-respirable, and fully recyclable.
How does Zerothermo solve edge thermal bridging in passive vaccine cooler box assemblies?
Thermal bridging at panel junctions is mitigated through precision CNC edge folding, overlapping stepped joints, and customized 6-sided panel box inserts. By eliminating direct linear air gaps between adjacent VIPs and integrating encapsulated barrier flaps, Zerothermo ensures uniform 3D thermal resistance across all box corners.
Are Zerothermo VIPs compliant with international Good Distribution Practice (GDP) & WHO PQS?
Yes. Zerothermo VIP products and assembled shipper boxes are designed to comply with ISTA 7D / 7E summer and winter ambient temperature challenge profiles, WHO PQS guidelines, and international Good Distribution Practice (GDP) standards for temperature-sensitive medicinal products.
Can panels be customized to fit custom cooler boxes and refrigerated air cargo containers?
Yes. We specialize in custom VIP dimensions ranging from Length 300–1200mm, Width 300–800mm, and Thickness 5–80mm. Special shapes including cylindrical wraps, slotted panels for curved walls, and cutout designs for sensor probes or latching mechanisms are routinely engineered and delivered.

Get In Touch

Request a Custom Quote & Thermal Consultation

Our technical engineering team can assist you with thermal holdover modeling, custom dimensions, sample testing requests, and global logistics quotations.

Email Inquiry
Email Contact: amanda@zerothermo.com
Direct Phone
Direct Phone / WhatsApp: +86-15892792306